Pete Gueldner
Vascular integrity,
from cells to tissue.
I investigate how cellular signaling remodels vascular matrix, and how matrix density, organization, and load sharing determine tissue strength and vulnerability.
Postdoctoral Associate · Biomedical Engineering · Yale University
Featured Projects
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![Fiber-network model of matrix loss and local mechanical weakness.]()
Matrix loss and local weakness
How matrix density and spatial organization alter load sharing, tissue strength, and local vulnerability.
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![Objective aneurysm sac isolation and the resulting vascular model.]()
Aneurysm geometry and mechanics
Repeatable aneurysm sac isolation for consistent geometric and biomechanical comparisons.
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![Clinical aortic image segmentation for patient-specific biomechanical analysis.]()
Image-based prediction
Combining vascular imaging, biomechanics, and machine learning to make predictions grounded in tissue mechanics.
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![Cell-regulated extracellular matrix remodeling, mechanobiological modeling, and predicted vascular state.]()
Cell-regulated matrix remodeling
Connecting cellular signaling, matrix remodeling, and models of growth and remodeling to vascular integrity.
Mentors
My research has been shaped by the mentorship of Jay Humphrey, David Vorp, Timothy Chung, and Ender Finol, spanning vascular biomechanics, experimental mechanics, and mechanobiological modeling.
